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GROMADA J, HOLST J J, RORSMAN P.Cellular regulation of islet hormone secretion by the incretin hormone glucagon-like peptide 1 [J]
The synbiotic combination provides both the probiotic bacteria and their preferred food source in a single formulation
Emerging evidence suggests GLP-1RAs may help in: Alzheimer Disease Reduced neuroinflammation Improved neuronal survival Potential slowing of cognitive decline Parkinson Disease Neuroprotective effects Reduced oxidative stress Improved neuronal signaling This area may redefine future neuroendocrine therapeutics

This also supports the finding that the cardiovascular benefits are not restricted to those agents structurally similar to human GLP-1 but are more likely a class effect that is seen in all GLP-1RAs

doi: 10.1152/ajprenal.00082.2009