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For instance, exenatide, the first GLP-1-analogue developed, demonstrated to promote human monocyte differentiation into alternatively activated M2 macrophages, leading to an increase in anti-inflammatory cytokines such as IL-10 while significantly reducing pro-inflammatory cytokines, including IL-6, TNF- and IL-1 ( Furthermore, GLP-1 has been hypothesised to act as a mediator between innate and adaptive immune responses

The same molecule, the same patent cliff, the same 250-million-strong pool of potential patients and six very different ways to make money off all of it

The answer, in almost every scenario, is that early dosing is preferable to missing a dose

When you fast, your insulin levels drop and your body switches to burning fat for fuel

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