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Weight loss of at least 5%10% is known to reduce complications of T2D and improve quality of life (Valdecantos et al., 2016)

Furthermore, in this same cohort, there were no significant differences in the rates of hospitalization for HF between the treatment and placebo groups

The target brain regions are part of the incentive salience network, suggesting a mechanism of de-linking the internal motivational drive associated with external craving stimuli

doi: 10.1136/bmj.38977.682025.2C

However, in a LIVE sub-study, myocardial glucose utilization did not improve in the liraglutide group as examined by F-fluorodeoxyglucose positron emission tomography [41], similar to a study using albiglutide [42]