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Methods Tests included several chromatography methods coupled with ultraviolet and mass spectrometry detectors, inductively coupled plasma optical emission spectroscopy, inductively coupled plasma mass spectrometry, nuclear magnetic resonance, dissolution analyses, in silico peptide/major histocompatibility complex II-binding prediction, and fibrillation assays

When activated, these receptors appear to dampen the dopamine-driven reward response that makes alcohol feel pleasurable and reinforcing effectively quieting the neurological "pull" toward drinking

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