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Disclosures/Conflicts of interest The authors whose names are listed immediately below certify that they have no affiliations with or involvement in any organization or entity with any financial interest or non-financial interest) in the subject matter or materials discussed in this article

JACC Basic Transl Sci 2016;1:267-76.PubMedPMC 25

Retatrutide peptide is a triple GLP-1/GIP/glucagon receptor agonist currently in late-stage clinical development

So the first thing is, and this goes to your point about PT and trainers and dieticians and is first asking somebody about their lived experience

Coupled by the fact that most insulin resistant weight loss patients in my practice eat a high carb low protein diet, so without correcting the protein deficiency and continuing to eat carbs their facial skin will become very saggy