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ENCORE-NF is a multicentre, randomised, placebo-controlled trial of patients with biopsy proven NASH and fibrosis, but not cirrhosis, that has completed enrollment

These symptoms occur most frequently during treatment initiation and dose escalation phases, typically diminishing in intensity as patients develop tolerance

Quick answer: GLP-1 receptor agonists (Ozempic, Wegovy) and the dual GLP-1/GIP agonist tirzepatide (Mounjaro, Zepbound) reduce obstructive sleep apnea severity primarily through weight loss
When youve achieved significant weight loss with medications like Ozempic or Wegovy, its a moment worth celebrating

The observations in SUSTAIN-6 are predictable, given that intensified versus conventional insulin therapy is well known to have the capacity to precipitate initial worsening of retinopathy in patients with T2D with advanced preexisting retinopathy, as shown in the Diabetes Control and Complications Trial (82)
