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They do not replace levothyroxine

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Researchers gave children two different doses of D-allulose (2.5 grams per 120 ml and 4.3 grams per 120 ml) and concluded, All in all, D-allulose was tolerated well in children, making this ingredient a good candidate to reformulate commercially produced goods by replacing added sugars with lower caloric content. 21 Stevia is extracted from the leaves of Stevia rebaudiana Bertoni, a shrub native to South America

As a retrospective cohort analysis, it is inherently subject to biases such as selection bias