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0.96%, in that order) [90]
However, weight loss itself, whether achieved through medication or lifestyle change, leads to reductions in both fat mass (FM) and lean mass (LM) , meaning that muscle and bone are often lost alongside fat
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Tirzepatide represents an important step in this direction, but further advances in triple agonism, oral formulations, and personalized medicine approaches will likely continue to reshape treatment paradigms
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