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43 In a phase 3 trial including patients with obesity (excluding T2DM), the highest dose group achieved a mean weight reduction of 11.2% by week 72

University of Oxford research paints an even clearer picture

If you plan to switch between GLP-1 medications, consult your healthcare provider first to ensure a safe transition

This is a trial or microdosing size: a 5mg vial holds two and a half 2mg starting doses, so most people move to a larger vial once they tolerate treatment

However, additional research is necessary to ensure these findings are reproducible, and the durability of fasting-induced weight loss without ongoing therapeutic support remains uncertain