non glp 1 drugs for weight loss with GLP-1 medicines does not result in a disproportionate loss of muscle mass or function in obese mice and humans If you aren't losing weight

Description

Leehey DJ, Singh AK, Alavi N, Singh R (2000) Role of angiotensin II in diabetic nephropathy

Many patients on semaglutide or tirzepatide consume far less than this because their appetite is so suppressed

While such a proximal-distal loop might indeed exist, it cannot be ruled out that while fewer in number, L-cells in the upper intestine are sufficient for the rapid induction of GLP-1 secretion following nutrient intake [[316], [317], [318]]

A significant reduction in alcohol intake was observed at follow-up compared with baseline, including among adults who were considered high alcohol consumers and drank more than 11 U alcohol per week at the start of the study