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109 The underlying mechanisms of epilepsy involve brain inflammation, mitochondrial dysfunction, and oxidative stress, all pathways that GLP-1 receptor agonists are known to target

It has been shown that GLP-1RA semaglutide can improve working and spatial memory in transgenic AD modelling APP/PS1/tau (3xTg) mice, promote the release of anti-inflammatory factors and inhibit the production of pro-inflammatory factors in the cerebral cortex and hippocampus, as well as reduce the deposition of -amyloid in the CA1 subfield of the hippocampus

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