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Oct 18: The gene therapy space celebrated another first on Wednesday, as the FDA cleared the way for the first-ever investigational in vivo CRISPR-based gene editing therapy to enter late-stage development

By enhancing gut barrier function, GLP-1 RAs cut off a major source of inflammation, the leaky gut, thus helping to resolve metabolic inflammation (107)

Paradoxically, in pancreas-specific Gpx4 knockout KC models or under high-iron diet conditions, ferroptosis instead facilitated tumorigenesis (140)

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