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Description
Phase 3 Results (REIMAGINE-2, Feb 2026): HbA1c reduction of up to 1.91 points, outperforming semaglutide alone Weight loss of up to 14.2% at 68 weeks in adults with type 2 diabetes and obesity In weight-management evaluation, diabetics achieved ~15.7% weight loss vs 3.1% with placebo Regulatory update: Novo Nordisk filed for FDA approval (Dec 2025) for weight management, supported by the REDEFINE clinical program

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DESCRIPTION: Retatrutide is an investigational peptide that activates three hormone receptors in the body namely the glucagon-like peptide-1 receptor the glucose-dependent insulinotropic peptide receptor and the glucagon receptor

Participants with diabetes treated with semaglutide did not show restored motivation

In its Phase 2 COURAGE obesity trial, the combination of []
