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GLP-1 and GIP/GLP-1 receptor agonists require refrigeration between 36F and 46F (2C to 8C) until first use
If your plan denies a claim, the appeal window is typically short and document-driven, so an organized paper trail is worth the effort up front

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Cold Storage and Access Challenges: The Final Hurdle in GLP-1 Availability While the FDA may determine that the national supply of tirzepatide and other GLP-1 medications is sufficient to meet market demand, the reality for patients often tells a different story
