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Description
Patients using Tirzepatide often report significant weight reductions, with many losing between 10% to 20% of their starting body weight within a year

Choquette AC, Bouchard L, Drapeau V, Lemieux S, Tremblay A, Bouchard C, Vohl MC, Perusse L

The release of proglucagon causes the liver to make glucose (gluconeogenesis converting protein to glucose) as well as to convert fatty acids into ketone bodies

& Weiss, J

In T2DM patients, insulin cannot regulate hepatic glycogen synthesis or glucose production, and increased hepatic gluconeogenesis is the primary cause of fasting hyperglycemia in T2DM [25]