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SCFAs are predominantly generated in the distal intestine, but they are also present in the ileum and are recognized for their ability to diminish glucose synthesis through a gut-brain axis

[DOI] [PMC free article] [PubMed] 489.Chen Q, Riviere JE, Lin Z

Baldini, G., Scherer, P

Notwithstanding, previous studies have documented beneficial effects of the activation of estrogen receptors in diet-induced obese females, by reducing body weight and fat accumulation and improving leptin resistance at central level 53,54

Could these medications replace bariatric surgery
