retatrutide glp-1 gip glucagon triple agonist mechanism GLP-1-based therapies for type 2 diabetes: from single, dual and triple agonists to endogenous GLP-1 production and L-cell differentiation retatrutide - Diabetes In Control
Description
Several uncertainties remain
Kabahizi A, et al
GLP-1 RAs are used for managing blood glucose levels in people with type 2 diabetes mellitus and have also been licensed for use in weight loss treatment
Acute Kidney Injury Due to Volume Depletion Inform patients of the potential risk of acute kidney injury due to dehydration associated with gastrointestinal adverse reactions
A 2023 SELECT trial determined that patients with pre-existing cardiovascular disease who used Wegovy over 39.8 months experienced the following events, compared to patients given a placebo
