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Therefore, drug delivery targeting the extracellular region of target receptors faces several insurmountable challenges, including (1) competitive interference from endogenous ligands or antibodies at the target and (2) pseudotarget or target loss caused by shedding or mutation of the extracellular region, which significantly inhibits drug efficacy and may pose safety concerns

Wireless motility capsule versus other diagnostic technologies for evaluating gastroparesis and constipation: a comparative effectiveness review

Tirzepatide is sometimes referred to as the next step after GLP-1 treatments, making patients think its a GLP-2 medication

Metformin and glucagon play opposing roles in the control of hepatic glucose production