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[DOI] [PMC free article] [PubMed] [Google Scholar] 56.Zunz E., La Barre J

Long-term dipeptidyl-peptidase 4 inhibition reduces atherosclerosis and inflammation via effects on monocyte recruitment and chemotaxis

doi: 10.1016/j.healun.2021.07.005

[2] Your GP may: Refer you to psychological services if anxiety symptoms are significant, including NHS Talking Therapies for anxiety and depression Consider whether anxiety treatment should be optimised before or alongside GLP-1 therapy, following NICE guidance for anxiety disorders Coordinate care with diabetes specialists, dietitians, and mental health professionals Review the risk-benefit balance of continuing GLP-1 treatment if mental health concerns arise Screen for and manage eating disorders according to NICE guidance before initiating or continuing weight-loss treatments Remember that GLP-1 medications are not a treatment for anxiety, and any mental health benefits are likely secondary to metabolic improvements

Semaglutide is an FDA-approved prescription medication with no psychoactive properties, and its use in the context of diabetes management or weight loss would not typically raise security concerns