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Racial and ethnic minorities carry a disproportionate burden of obesity and T2D in the general population, but their enrolment in the completed tirzepatide trials was lower than expected, which raises concerns regarding the generalizability of these trials

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When GLP-1 signaling improves: Appetite decreases Blood sugar stabilizes Gastric emptying slows Cravings reduce The result is your body starts to work with you again, instead of against you

Moreover, incorporating unnatural amino acids can reduce peptide drugs immunogenicity, as the human immune system primarily recognizes peptide segments composed of L-amino acids