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Increasing attention has been directed toward the concept of a therapeutic window of opportunity, which frames early PsA as a transitional phase characterized by musculoskeletal symptoms such as arthralgia, dactylitis, and subclinical enthesitis in patients with PsO, often preceding clinically evident arthritis (12)

HDV is a severe, fastprogressing viral infection

& Morton, J
Peripheral mechanisms appear to account for many of tirzepatide's metabolic effects

Reprod Biomed Online 35(1):121127
