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J Psychiatr Pract
Patients receiving oral semaglutide had significantly higher risk of treatment discontinuation due to side effects (RR: 1.79, 95% CI: 1.13 to 2.83)

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These shifts are usually small and mild in people without heart disease

Insulin sensitivity improvements typically emerge within 2-4 weeks, while peak weight loss effects are usually observed after 12-16 weeks of consistent therapy
