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Table 1 Physical activity recommendations in people with obesity on GLP-1RAs

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Published Phase 2 data (Jastreboff et al., NEJM 2023, N=338) demonstrated that Retatrutide at 12mg achieved 24.2% mean body weight reduction at 48 weeks surpassing Tirzepatides 22.5% achieved in 24 additional weeks

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Both these strategies are found to be successful in overcoming deficiencies of endogenous GLP-1 or providing supra-physiological levels of GLP-1

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physical activity monitoring and weight measurement) is crucial to the achievement of health behaviour goals (Fig

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This includes adopting a healthier diet and more exercise

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