glp-1 medications cost Administration announces deal to lower prices The Rising Cost and Use
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AstraZeneca, Sep 2022

a , Close-up view of R299 of ECL2 modelled into the density map at low threshold shows that the Arg side chain reaches into the GLP-1 binding pocket in close proximity to H7 and T11 of the peptide

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Because GLP-1 is quickly broken down by enzymes like DPP-4, only a small fraction remains active
