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Incretin hormones include glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP)

Some doctors also worry the new coverage could spark a surge in demand that will strain busy clinics and pharmacies, and others raised concerns about a lack of broader public awareness of the program

Recent findings from the SUSTAIN-7 study demonstrated semaglutide's superiority over dulaglutide in enhancing glycaemic management and facilitating significant weight reduction, while preserving similar safety profiles (Pratley et al

Obesity is the entry point, but cardiovascular disease, kidney disease, MASH, sleep apnea, and metabolic syndrome may define the long-term value

This increased activity is strongly associated with HbA1c, the level reflecting average blood sugar over weeks