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The mean weight loss among patients prescribed GLP-1 analogue monotherapy at 12 months was 11.42kg, SD 9.95 (9.6% TBWL)

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Tirzepatide was more efficacious in reducing body weight

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In a study published in NEJM SURMOUNT 5*, an international comparative open-label, controlled trial, adult participants with obesity but without type 2 diabetes the 2 agents were compared in maximally tolerated recommended doses

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