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The SURMOUNT-1 study was a placebo-controlled 72-week trial in obese subjects that randomized 2,539 participants without diabetes into four equally large study arms with placebo or one of the three tirzepatide doses (5, 10, or 15 mg once weekly)

This can aid in maintaining balanced blood sugar levels and managing appetite

For most people on GLP-1s, yes - especially early on

However, this is in direct contradiction with other reports that identified the paraventricular hypothalamic nucleus as required in the control of food intake via CNSderived GLP1 (Liu et al., 2017)