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GIP receptor activation enhances insulin sensitivity and promotes visceral fat metabolism

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Frias et al., The Lancet, 2021 (SURPASS-2) Targets Two Key Aging Pathways By activating both GLP-1 and GIP pathways, Tirzepatide offers a more comprehensive approach to reversing metabolic aging compared to single-agonist therapies

Additional Considerations For adults, common side effects can include: Changes in taste Tingling or numbness on the skin Insomnia Constipation Dry mouth For children, common side effects can include: Depression Dizziness Muscle aches and pains Fever Do not start Qsymia if you: Are pregnant or thinking of becoming pregnant, or are breastfeeding Have glaucoma Have hyperthyroidism Have an allergy or sensitivity to any of the ingredients in Qsymia Are currently taking an MAOI or have taken one within two weeks When starting Qsymia, watch for any changes in your mood

These include cases of pancreatitis and a potential association with thyroid C-cell tumors in rodent models