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Clinical trials have demonstrated substantial weight losswith mean reductions up to approximately 21% of body weight at 72 weeks in the SURMOUNT-1 trialalongside meaningful improvements in hemoglobin A1c levels in patients with diabetes

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In findings from the STEP TEENS phase 3a trial, adolescents aged 12 to 17 years with obesity or overweight and at least one weight-related coexisting condition were randomly assigned 2:1 to receive semaglutide 2.4 mg (Wegovy, Novo Nordisk) or placebo for 68 weeks

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