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Progressive overload, meaning gradually increasing weight or volume over time, signals the body to maintain and build muscle even during caloric deficit
TCF7L2 variant rs7903146 affects the risk of type 2 diabetes by modulating incretin action

Eating carbohydrates first is less effective
Meanwhile, Eli Lilly is gearing up to introduce orforglipron calcium, which is expected to hit the market by 2026

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