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[DOI] [PubMed] [Google Scholar] 238.Min SH, Yoon JH, Hahn S, Cho YM

Regul Pept 114(2-3):115121

This improves tolerability, as gastrointestinal effects are most severe at initiation and generally wane over time
This is often attributed to the medications ability to: Lower systemic inflammation Reduce blood pressure Improve blood sugar control (reducing the sugar stress on kidney filters) Decrease albuminuria (the presence of excess protein in the urine, which is a marker of kidney damage) For someone with a history of stones, this is generally positive news
There are lots of good options
