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It was put down to having an infection

Dysfunction in GLP-1R signaling has been implicated in multiple pathologies, including type 2 diabetes mellitus (T2DM), obesity, atherosclerosis, Parkinsons disease (PD), Alzheimers disease (AD), non-alcoholic steatohepatitis (NASH), and several cancers

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GLP-1 non responders are patients who do not achieve expected improvements in blood sugar or weight despite appropriate therapy
