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GLP-1 receptor agonists bind to GLP-1 receptors on pancreatic beta cells, stimulating glucose-dependent insulin secretion whilst simultaneously suppressing glucagon release from alpha cells

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Available online: [DOI] [PubMed] [Google Scholar] 46.Tremblay I., Par E., Arsenault D., Douziech M., Boucher M.J

Kidney effects of Glucagon-Like Peptide 1 (GLP1): from molecular foundations to a pharmacophysiological perspective DOI: 10.1590/2175-8239-JBN-2024-0101pt Graphical Abstract Click to view Abstract GLP1 receptor agonists (GLP1-RAs) are drugs that mimic the effects of the incretin hormone GLP1 and were initially introduced in medicine for the treatment of diabetes in 2005 and for obesity in 2014