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4-8 Weeks and Beyond: As semaglutide GLP-1 continues to work within the system, the most substantial appetite reduction typically occurs between 4 to 8 weeks of use
Those are potentially two phenotypes
Li Y, Chigurupati S, Holloway H, et al
Why Effects Extend Beyond Blood Sugar The broad benefits of GLP-1 medications stem from addressing underlying metabolic dysfunction rather than just treating elevated glucose: Weight loss addresses root causes: Excess weight drives insulin resistance, the core problem in Type 2 diabetes
