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DiLeone, meanwhile, said the dosing was consistent with those used in other comparable research efforts, and should not have caused significant aversion in mice beyond the first day

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107 Subsequent in vivo studies employing a more advanced cocktail (GATA4, HAND2, MEF2C, and TBX5, also known as GHMT) successfully induced cardiac fibroblasts to transdifferentiate into cardiomyocytes post-MI, thereby restoring electromechanical function