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Depressed patients commonly exhibit: 01 Abnormal cortisol rhythms: Delayed morning cortisol peaks or flattened circadian rhythms, leading to hippocampal volume reduction and synaptic plasticity impairment

By nature Im a morning person, 5-530am Im up and going

Masheb, R., & White, M

Phosphorylation levels were normalized to total protein levels and expressed relative to the response induced by insulin following a 5-minute treatment
