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For example, rats administered exendin-4 into the HPCv only decrease their consumption of a high fat/sugar diet 6h after the infusion, but at the 24h timepoint chow intake is also reduced [69]

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In some cases, hospitalization was required, although most have responded to outpatient management with antiemetic and prokinetic agents

Youre activating two separate systems that work together rather than piling more stimulation onto the same receptors