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Description
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Combination therapy with SGLT2 inhibitors + GLP-1 RAs may reduce cardiorenal risk and CV & all-cause mortality in T2D vs SGLT22 inhibitor and GLP-1 RA monotherapy
That gap - plus verified pricing on compounded semaglutide and tirzepatide, and an FDA deadline that hits June 29 - is exactly what this guide is for.
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In contrast, no benefits on the rate of decline in glomerular filtration rate have been seen in trials of DPP-4 inhibitors, perhaps because the renal actions of DPP-4 inhibitors are primarily mediated by potentiation of SDF-1, not GLP-1
