glp 1 cardiovascular disease GLP-1: A Game-Changer for Heart Health in Obesity GLP-1 receptor agonists and myocardial

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Mediators of Inflammation

A recent multicenter international phase II RCT (GOLDEN-505) in noncirrhotic biopsy-proven NASH patients showed an insignificant difference in NASH resolution without fibrosis progression between the elafibranor and placebo groups at 52 weeks of treatment

26 The majority (67%) of the patients reviewed had a mean baseline HbA1c of 9.5% when therapy was initiated, which supports the theory of lack of action in response to abnormal findings