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To improve the pharmacokinetic profile and further explore the therapeutic potential of such an endogenously based GLP-1R/GcgR co-agonist, a DPP-IV-resistant OXM analogue was developed by adding a d-stereoisomer of serine at position 2 and a cholesterol moiety to the C-terminal domain

All FDA-approved GLP-1 medications are administered via subcutaneous injection or oral tablets, requiring prescription from licensed healthcare providers

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Added sugars are those added during food processing (CDC 2024)