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2007 Oct;61(10):1777-8 )

The GLP-1 receptor agonist semaglutide reduces risks of kidney function loss, kidney failure, cardiovascular events, cardiovascular death and all-cause mortality in people with chronic kidney disease and type 2 diabetes

Gastrointestinal and Gallbladder Effects Gastrointestinal symptoms are usually dose-related and may be mitigated by slower titration and taking smaller, lower-fat meals during the first weeks

This approach addresses the underlying symptom of insulin resistance in type 2 diabetes, setting Mounjaro apart from other treatments like Semaglutide and liraglutide, which lack the additional benefit of GIP activation

View Our Interactive Dashboard on GLP-1RA Therapies in Development (Free Excel Available) Lilly, Hanmi work on triple agonists