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These risk differences might be explained by additional mechanisms beyond the actions of GLP-1 RAs on vasculature, including the chronotropic effects of GLP-1 RAs which may blunt cardiac protection ( Unstable angina pectoris: An umbrella review of meta-analyses of RCTs including 56,004 patients with diabetes, prediabetes, and at high risk of diabetes, found no association between GLP-1 RAs and the risk of uAP (RR = 1.06, 95%CI = 0.931.21) when compared to placebo (Zhu et al., 2020)

doi: 10.3389/fmed.2021.695792

doi: 10.1002/osp4.342 41 WangGWuPQiuYDongXWangYChiYet al

[DOI] [PubMed] [Google Scholar] 36.Vahl T.P., Paty B.W., Fuller B.D., Prigeon R.L., DAlessio D.A

Digestive enzymes are proteins made in the stomach, small intestine, and pancreas that break down food and help digestion