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When rheumatologists use them for inflammatory arthritis, it is considered off-label prescribing a legal and common practice when supported by emerging clinical evidence and individualized patient need

Serious adverse events like pancreatitis or gallbladder disease remain rare but require immediate medical attention

Strategies to Minimize Interaction Risks To reduce the chances of problems linked to drug interactions its recommended to keep a record of each patients medications routinely assess how well the medications work and their safety and make changes to treatments as needed depending on clinical assessment and how the patient is responding

& Culotti, J

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