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If you experience reduced exercise capacity, diminished strength gains, or prolonged fatigue despite adequate nutrition, reducing or eliminating creatine may help you reassess whether your training volume aligns with your current energy intake and tirzepatide dosing

Neither approach changes the total amount of tirzepatide in the vial

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I have felt ZERO icky side effects

For tirzepatide, this principle applies with extra force because peptide degradation is invisible, unpredictable without laboratory testing, and can affect not just potency but also your body immune response to the medication
