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Using a global dataset and propensity matching, they found significantly lower mortality rates, major cardiovascular events (MACEs), and adverse kidney outcomes (MAKEs) among GLP-1 RA users compared to non-users

Introduction Significant reductions in cardiovascular events, all-cause mortality, and the advancement of kidney disease are demonstrated by important studies such as FLOW

CivicScience offers insights into the impact of cost, side effects & trends in GLP-1 usage.

A review by Frank Duca and graduate students Hallie Wachsmuth and Savanna Weninger at the University of Arizona, Tucson, USA, reveals a more complicated picture, with many different interacting neural and hormonal signals, with increasing evidence for the vital role played by the microbes in the gastrointestinal tract

Although, in the last 10 years, the use of GLP-1 RAs, especially semaglutide and liraglutide, has increased, its clinical implications and how it affects metabolic parameters have yet to be fully consolidated