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Before initiating SGLT2 inhibitor therapy one should assess renal function and volume status

Use caution when initiating or escalating doses of liraglutide injection in patients with renal impairment [see Use in Specific Populations (8.6)]

The NHS advises drinking no more than 14 units of alcohol per week, spread over three or more days, with several alcohol-free days each week
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Doing so can cause serious side effects, including an increase in seizure frequency or severe withdrawal symptoms
