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SCFAs can affect the integrity of the intestinal mucosa, glucose and lipid metabolism, immune system, and inflammatory responses

Clinical trials evaluating semaglutide safety, including the SUSTAIN and STEP trial programs which enrolled thousands of participants, did not identify UTIs as a significant adverse event associated with the medication

The first peptide described with incretin activity was the gastric inhibitory polypeptide (GIP) that went on to be referred to also as the glucose-dependent insulinotropic polypeptide GIP)

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Giambartolomei, C