what are the side effects of glp-1 medications Receptor Agonists GLP-1 Medications Infographic | Medidex

For example, patients who experience significant side effects with once-weekly semaglutide might tolerate once-daily liraglutide better, or vice versa

Serious adverse events and complications of these medications may include Gastroparesis (paralysis of the stomach), NAION vision loss, Ileus, Pancreatitis, Wernickes Encephalopathy, Bowel obstruction (blocked intestine), Malnutrition requiring hospitalization, and Pulmonary aspiration while under anesthesia or during surgery

GLP-1 receptor agonists (semaglutide) and dual GLP-1/GIP receptor agonists (tirzepatide) do not directly cause muscle wasting

described the activation of mammalian target of rapamycin (mTOR) as a crucial pathway for neuron protection, and that GLP-1RA affects mTOR activity by reducing caspase-3 and caspase-8 (51)

These medications work by mimicking the action of endogenous GLP-1, binding to GLP-1 receptors found throughout the body, particularly in the pancreas, brain, and gastrointestinal tract