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Mounjaro is FDA-approved to: Control blood sugar levels in adults and children ages 10+ with type 2 diabetes mellitus Zepbound is FDA-approved to: Reduce excess body weight and manage weight long term in adults with obesity or overweight who have at least one weight-related health condition (e.g

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It functions as a GLP-1 agonist by imitating the actions of GLP-1 to keep blood sugar levels steady and suppress hunger

doi: 10.1161/CIRCULATIONAHA.125.074545 Summary Keywords cardiovascular outcomes, SGLT2 inhibitors, GLP-1 agonists, combination therapy, heart failure, renal outcomes Citation Aristizbal-Colorado D, Corredor-Rengifo D, Sierra-Castillo S, Lpez-Corredor C, Vernaza-Trujillo D-A, Weir-Restrepo D, Izquierdo-Condoy JS, Ortiz-Prado E, Rico-Fontalvo J, Gmez-Mesa J-E, Abreu-Lomba A and Rivera-Martnez W-A (2025) A decade of progress in type 2 diabetes and cardiovascular disease: advances in SGLT2 inhibitors and GLP-1 receptor agonists a comprehensive review