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EMANATE: a study of setmelanotide in patients with specific gene variants in the MC4R pathway(2021)
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When you lose weight rapidly on a GLP-1 medication, the breakdown of fat releases purines into the bloodstream, which convert to uric acid
However, tirzepatide works on 2 receptors, GLP-1 and GIP
But GLP-1 drugs are meant to be taken long-term, not just for an event, both Levy and McGowan emphasize, warning that stopping or interrupting therapy can lead weight regain and increased side effects
